Issue 17, 2007

Conformational control of HCl co-transporter: imidazole functionalised isophthalamidevs. 2,6-dicarboxamidopyridine

Abstract

Replacement of the central isophthalamide core in a synthetic HCl receptor, with a 2,6-dicarboxamidopyridine, leads to a more preorganised molecular structure that exhibits higher chloride affinity and membrane transport flux.

Graphical abstract: Conformational control of HCl co-transporter: imidazole functionalised isophthalamide vs. 2,6-dicarboxamidopyridine

Supplementary files

Article information

Article type
Communication
Submitted
05 Mar 2007
Accepted
27 Mar 2007
First published
04 Apr 2007

Chem. Commun., 2007, 1736-1738

Conformational control of HCl co-transporter: imidazole functionalised isophthalamide vs. 2,6-dicarboxamidopyridine

P. A. Gale, J. Garric, M. E. Light, B. A. McNally and B. D. Smith, Chem. Commun., 2007, 1736 DOI: 10.1039/B703259E

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