Issue 20, 2007
From the journal:

Chemical Communications

Promiscuous zinc-dependent acylase-mediated carbon–carbon bond formation in organic media†

Jian-Ming Xu,a   Fu Zhang,a   Bo-Kai Liu,a   Qi Wua  and  Xian-Fu Lin*a  

* Corresponding authors

a Department of Chemistry, Zhejiang University, Hangzhou 310027, People's Republic of China
E-mail: llc123@zju.edu.cn
Fax: 86 571 87952618
Tel: 86 571 87951588

Abstract

A zinc-dependent acylase, D-aminoacylase from Escherichia. Coli, displays a promiscuous activity to catalyze the carbon–carbon bond formation reaction of 1,3-dicarbonyl compounds to methyl vinyl ketone in organic media.

Graphical abstract: Promiscuous zinc-dependent acylase-mediated carbon–carbon bond formation in organic media

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Article information

DOI
https://doi.org/10.1039/B700327G
Article type
Communication
Submitted
09 Jan 2007
Accepted
01 Feb 2007
First published
22 Feb 2007

Chem. Commun., 2007, 2078-2080

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Promiscuous zinc-dependent acylase-mediated carbon–carbon bond formation in organic media

J. Xu, F. Zhang, B. Liu, Q. Wu and X. Lin, Chem. Commun., 2007, 2078 DOI: 10.1039/B700327G

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