Issue 42, 2006
From the journal:

Chemical Communications

Water soluble distyryl-boradiazaindacenes as efficient photosensitizers for photodynamic therapy†

Serdar Atilgan,a   Zeynep Ekmekci,a   A. Lale Dogan,b   Dicle Gucb  and  Engin U. Akkaya*a  

* Corresponding authors

a Department of Chemistry, Middle East Technical University, Ankara, Turkey
E-mail: akkayaeu@metu.edu.tr
Fax: 90 312 210-3200
Tel: 90 312 210-5126

b Department of Basic Oncology, Oncology Institute, Hacettepe University, Sihhiye, Ankara, Turkey

Abstract

We introduce a novel class of water soluble, extended conjugation boradiazaindacene dyes which are efficient singlet oxygen generators and have spectacular photoinduced cytotoxicity when excited in the “therapeutic window” of the electromagnetic spectrum.

Graphical abstract: Water soluble distyryl-boradiazaindacenes as efficient photosensitizers for photodynamic therapy

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Article information

DOI
https://doi.org/10.1039/B612347C
Article type
Communication
Submitted
29 Aug 2006
Accepted
22 Sep 2006
First published
06 Oct 2006

Chem. Commun., 2006, 4398-4400

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Water soluble distyryl-boradiazaindacenes as efficient photosensitizers for photodynamic therapy

S. Atilgan, Z. Ekmekci, A. L. Dogan, D. Guc and E. U. Akkaya, Chem. Commun., 2006, 4398 DOI: 10.1039/B612347C

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