Issue 40, 2006

The reductive amination of aldehydes and ketones by catalytic use of dibutylchlorotin hydride complex

Abstract

The reductive amination of aldehydes or ketones using Ph2SiH2 or PhSiH3 has been effectively promoted by the direct use of Bu2SnClH–pyridine N-oxide as a catalyst; this method has advantages in terms of its mild conditions and wide application to various carbonyls and amines, including aliphatic examples.

Graphical abstract: The reductive amination of aldehydes and ketones by catalytic use of dibutylchlorotin hydride complex

Supplementary files

Article information

Article type
Communication
Submitted
25 Jul 2006
Accepted
14 Aug 2006
First published
29 Aug 2006

Chem. Commun., 2006, 4189-4191

The reductive amination of aldehydes and ketones by catalytic use of dibutylchlorotin hydride complex

H. Kato, I. Shibata, Y. Yasaka, S. Tsunoi, M. Yasuda and A. Baba, Chem. Commun., 2006, 4189 DOI: 10.1039/B610614E

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