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Issue 25, 2006
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Extended ethidium bromide analogue as a triple helix intercalator: synthesis, photophysical properties and nucleic acids binding

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Abstract

Ethidium bromide has been extended by fusing an additional aromatic ring resulting in a larger intercalator with increased affinity for poly r(A)·r(U), poly d(A)·d(T) and triple helices when compared to the parent heterocycle.

Graphical abstract: Extended ethidium bromide analogue as a triple helix intercalator: synthesis, photophysical properties and nucleic acids binding

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Publication details

The article was received on 23 Mar 2006, accepted on 10 May 2006 and first published on 26 May 2006


Article type: Communication
DOI: 10.1039/B604281C
Chem. Commun., 2006, 2684-2686

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    Extended ethidium bromide analogue as a triple helix intercalator: synthesis, photophysical properties and nucleic acids binding

    V. K. Tam, Q. Liu and Y. Tor, Chem. Commun., 2006, 2684
    DOI: 10.1039/B604281C

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