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Issue 6, 2006

Lithocholic acid analogues, new and potent α-2,3-sialyltransferase inhibitors

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Abstract

A new type of noncompetitive α-2,3-sialyltransferase inhibitor has been synthesized; we report the discovery, preparation and inhibitory activity of sixteen lithocholic acid analogues.

Graphical abstract: Lithocholic acid analogues, new and potent α-2,3-sialyltransferase inhibitors

Supplementary files

Article information


Submitted
20 Oct 2005
Accepted
08 Dec 2005
First published
09 Jan 2006

Chem. Commun., 2006, 629-631
Article type
Communication

Lithocholic acid analogues, new and potent α-2,3-sialyltransferase inhibitors

K. Chang, L. Lee, J. Chen and W. Li, Chem. Commun., 2006, 629 DOI: 10.1039/B514915K

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