Issue 19, 2005

A synthesis of multisubstituted vinylsilanes via ynolates: stereoselective formation of β-silyl-β-lactones followed by decarboxylation

Abstract

(Z)-Selective synthesis of multisubstituted vinylsilanes was achieved by stereoselective protonation or alkylation of β-silyl-β-lactone enolates, prepared by cycloadditions of acylsilanes with ynolates, followed by decarboxylation.

Graphical abstract: A synthesis of multisubstituted vinylsilanes via ynolates: stereoselective formation of β-silyl-β-lactones followed by decarboxylation

Supplementary files

Article information

Article type
Communication
Submitted
07 Dec 2004
Accepted
10 Mar 2005
First published
29 Mar 2005

Chem. Commun., 2005, 2477-2479

A synthesis of multisubstituted vinylsilanes via ynolates: stereoselective formation of β-silyl-β-lactones followed by decarboxylation

M. Shindo, K. Matsumoto and K. Shishido, Chem. Commun., 2005, 2477 DOI: 10.1039/B418310J

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