Issue 11, 2005
From the journal:

Chemical Communications

Lysine–enediyne conjugates as photochemically triggered DNA double-strand cleavage agents†

Serguei V. Kovalenkoa  and  Igor V. Alabugin*a  

* Corresponding authors

a Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306-4390, USA, USA
E-mail: alabugin@chem.fsu.edu
Fax: +1 850 644 8281
Tel: +1 850 644 5795

Abstract

Statistical analysis of DNA-photocleavage by two types of lysine–enediyne conjugates confirms that more double-strand breaks are produced than can be accounted for by coincident single-strand breaks.

Graphical abstract: Lysine–enediyne conjugates as photochemically triggered DNA double-strand cleavage agents

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Article information

DOI
https://doi.org/10.1039/B417012A
Article type
Communication
Submitted
10 Nov 2004
Accepted
23 Dec 2004
First published
25 Jan 2005

Chem. Commun., 2005, 1444-1446

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Lysine–enediyne conjugates as photochemically triggered DNA double-strand cleavage agents

S. V. Kovalenko and I. V. Alabugin, Chem. Commun., 2005, 1444 DOI: 10.1039/B417012A

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