Issue 6, 2005

Synthesis and establishment of stereochemistry of the unusual polyoxazole–thiazole based cyclopeptide YM-216391 isolated from Streptomyces nobilis

Abstract

A concise total synthesis of the unusual oxazole-based cyclopeptide structure YM-216391, which also establishes the stereochemistry of the natural product i.e.1, is described.

Graphical abstract: Synthesis and establishment of stereochemistry of the unusual polyoxazole–thiazole based cyclopeptide YM-216391 isolated from Streptomyces nobilis

Article information

Article type
Communication
Submitted
28 Oct 2004
Accepted
19 Nov 2004
First published
23 Dec 2004

Chem. Commun., 2005, 797-799

Synthesis and establishment of stereochemistry of the unusual polyoxazole–thiazole based cyclopeptide YM-216391 isolated from Streptomyces nobilis

J. Deeley and G. Pattenden, Chem. Commun., 2005, 797 DOI: 10.1039/B416530F

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