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Issue 13, 2004
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Developing novel activity-based fluorescent probes that target different classes of proteases

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Abstract

In this article, we report the design and synthesis of a group of novel activity-based probes that target different protease sub-classes based on their substrate specificities, rather than their enzymatic mechanisms. The feasibility of our approach has been demonstrated by using representative members of the different protease sub-classes.

Graphical abstract: Developing novel activity-based fluorescent probes that target different classes of proteases

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Supplementary files

Article information


Submitted
24 Mar 2004
Accepted
27 Apr 2004
First published
01 Jun 2004

Chem. Commun., 2004, 1512-1513
Article type
Communication

Developing novel activity-based fluorescent probes that target different classes of proteases

Q. Zhu, A. Girish, S. Chattopadhaya and S. Q. Yao, Chem. Commun., 2004, 1512
DOI: 10.1039/B404471A

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