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Issue 5, 2003
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Alkaline salt-catalyzed aza Diels–Alder reactions of Danishefsky’s diene with imines in water under neutral conditions

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Abstract

Two- or three-component aza Diels–Alder reactions of Danishefsky’s diene with imines or aldehydes and amines in water took place smoothly under neutral conditions in the presence of a catalytic amount of an alkaline salt such as sodium triflate to afford dihydro-4-pyridones in high yields.

Graphical abstract: Alkaline salt-catalyzed aza Diels–Alder reactions of Danishefsky’s diene with imines in water under neutral conditions

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Article information


Submitted
22 Jan 2003
Accepted
03 Feb 2003
First published
11 Feb 2003

Chem. Commun., 2003, 574-575
Article type
Communication

Alkaline salt-catalyzed aza Diels–Alder reactions of Danishefsky’s diene with imines in water under neutral conditions

C. Loncaric, K. Manabe and S. Kobayashi, Chem. Commun., 2003, 574
DOI: 10.1039/B300880K

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