Issue 6, 2002
From the journal:

Chemical Communications

Hydroxy-substituted oligopyridine dicarboxamide helical foldamers

Ivan Huc,*a   Victor Maurizot,a   Heinz Gornitzkab  and  Jean-Michel Légerc  

* Corresponding authors

a Institut Européen de Chimie et Biologie, 16 av. Pey Berland, Pessac Cedex, France
E-mail: i.huc@iecb-polytechnique.u-bordeaux.fr

b Laboratoire d’Hétérochimie Fondamentale et Appliquée, Université Paul Sabatier, 118 route de Narbonne, Toulouse Cedex 4, France

c Laboratoire de Pharmacochimie, Université Victor Segalen Bordeaux II, 146 rue Léo Saignat, Bordeaux, France

Abstract

As shown by X-ray diffraction and NMR studies, short oligopyridine dicarboxamides bearing benzyloxy, hydroxy and hydroxylate moieties adopt very robust single helical conformations, even in water.

Graphical abstract: Hydroxy-substituted oligopyridine dicarboxamide helical foldamers

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Article information

DOI
https://doi.org/10.1039/B111612F
Article type
Communication
Submitted
21 Dec 2001
Accepted
08 Feb 2002
First published
22 Feb 2002

Chem. Commun., 2002, 578-579

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Hydroxy-substituted oligopyridine dicarboxamide helical foldamers

I. Huc, V. Maurizot, H. Gornitzka and J. Léger, Chem. Commun., 2002, 578 DOI: 10.1039/B111612F

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