Jump to main content
Jump to site search

Issue 19, 2001
Previous Article Next Article

Highly efficient oligosaccharide synthesis on water-soluble polymeric primers by recombinant glycosyltransferases immobilised on solid supports

Author affiliations

Abstract

Recombinant β-1,4-galactosyltransferase (β1,4-GalT) and α-2,6-sialyltransferase (α2,6-SiaT) immobilised covalently with activated Sepharose beads were employed for the practical synthesis of a trisaccharide derivative, Neu5Acα(2→6)Galβ(1→4)GlcNAcβ-O-(CH2) 6-NH2, on a water-soluble primer having GlcNAc residues through a α-chymotrypsin-sensitive linker.

Back to tab navigation

Article information


Submitted
04 Jun 2001
Accepted
15 Aug 2001
First published
17 Sep 2001

Chem. Commun., 2001, 1944-1945
Article type
Communication

Highly efficient oligosaccharide synthesis on water-soluble polymeric primers by recombinant glycosyltransferases immobilised on solid supports

S. Nishiguchi, K. Yamada, Y. Fuji, S. Shibatani, A. Toda and S. Nishimura, Chem. Commun., 2001, 1944
DOI: 10.1039/B104896C

Social activity

Search articles by author

Spotlight

Advertisements