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Issue 4, 2001
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First anti-oestrogen in the cyclopentadienyl rhenium tricarbonyl series. Synthesis and study of antiproliferative effects

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Abstract

A route to the organometallic complex 8 is described, along with a study of its antiproliferative effects on breast cancer cell lines; in the examples studied, 8 behaves in a very similar manner to tamoxifen, suggesting new possibilities for applications in organometallic chemistry.

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Article information


Submitted
28 Nov 2000
Accepted
18 Jan 2001
First published
08 Feb 2001

Chem. Commun., 2001, 383-384
Article type
Communication

First anti-oestrogen in the cyclopentadienyl rhenium tricarbonyl series. Synthesis and study of antiproliferative effects

G. Jaouen, S. Top, A. Vessières, P. Pigeon, G. Leclercq and I. Laios, Chem. Commun., 2001, 383
DOI: 10.1039/B009553M

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