Issue 2, 2001

Preparation and determination of X-ray-crystal and NMR-solution structures of γ2,3,4-peptides

Abstract

(R,R,R)-γ-Amino acids with side chains in the 2-, 3-, and 4-positions, prepared by addition of acyloxazolidinones to a nitroolefin and hydrogenation, have been coupled to γ- tetra-, and γ-hexapeptides which are shown to form (M)-2.614 helices in the crystal state and in MeOH solution.

Supplementary files

Article information

Article type
Communication
Submitted
17 Oct 2000
Accepted
27 Nov 2000
First published
04 Jan 2001

Chem. Commun., 2001, 207-208

Preparation and determination of X-ray-crystal and NMR-solution structures of γ2,3,4-peptides

D. Seebach, M. Brenner, M. Rueping, B. Schweizer and B. Jaun, Chem. Commun., 2001, 207 DOI: 10.1039/B008377L

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