Issue 24, 2000

Polycyclitols. Novel conduritol and carbasugar hybrids as a new class of potent glycosidase

Abstract

We have conceptualized new molecular entities (bicyclitols) in which two conduritol and two carbasugar moieties are embedded in a polyhydroxylated decahydronaphthalene framework and achieved their syntheses in a stereo- and regioselective manner. One of the bicyclitols was found to be a potent and selective α-glucosidase inhibitor.

Article information

Article type
Communication
Submitted
06 Sep 2000
Accepted
31 Oct 2000
First published
22 Nov 2000

Chem. Commun., 2000, 2429-2430

Polycyclitols. Novel conduritol and carbasugar hybrids as a new class of potent glycosidase inhibitors

G. Mehta and S. S. Ramesh, Chem. Commun., 2000, 2429 DOI: 10.1039/B007224I

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