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Issue 24, 2000
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Polycyclitols. Novel conduritol and carbasugar hybrids as a new class of potent glycosidase

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Abstract

We have conceptualized new molecular entities (bicyclitols) in which two conduritol and two carbasugar moieties are embedded in a polyhydroxylated decahydronaphthalene framework and achieved their syntheses in a stereo- and regioselective manner. One of the bicyclitols was found to be a potent and selective α-glucosidase inhibitor.

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Publication details

The article was received on 06 Sep 2000, accepted on 31 Oct 2000 and first published on 22 Nov 2000


Article type: Communication
DOI: 10.1039/B007224I
Chem. Commun., 2000, 2429-2430

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    Polycyclitols. Novel conduritol and carbasugar hybrids as a new class of potent glycosidase inhibitors

    G. Mehta and S. S. Ramesh, Chem. Commun., 2000, 2429
    DOI: 10.1039/B007224I

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