Issue 23, 2000

Development of small peptides recognizing a monosaccharide by combinatorial chemistry

Abstract

Small peptides selected from a library of 62000 chemically synthesized peptides were able to recognize a monosaccharide specifically and efficiently using both sandwiching and hydrogen bonding interactions, much like sugar-binding proteins (lectins) with the appropriate orientation of amino acid side chains.

Article information

Article type
Communication
Submitted
18 Aug 2000
Accepted
09 Oct 2000
First published
07 Nov 2000

Chem. Commun., 2000, 2295-2296

Development of small peptides recognizing a monosaccharide by combinatorial chemistry

N. Sugimoto, D. Miyoshi and J. Zou, Chem. Commun., 2000, 2295 DOI: 10.1039/B006714H

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