Issue 13, 2000
From the journal:

Chemical Communications

A new diastereoselective approach to simplified Dynemicin analogues

Giuseppe Guanti*a  and  Renata Riva*a  

* Corresponding authors

a Università di Genova, Dipartimento di Chimica e Chimica Industriale, and, C.N.R., CSCCCA, via Dodecaneso 31, I-16146, Genova, Italy.
E-mail: guanti@chimica.unige.it, riva@chimica.unige.it

Abstract

The stereoselective synthesis of new simplified Dynemicin analogues is reported: key steps of the sequence are the regio- and diastereo-selective functionalization of a quinoline nucleus, bearing a substituent with a stereogenic centre, and the formation of the 10-membered cyclic enediyne system by Pd-catalyzed Stille-like reaction.

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Article information

DOI
https://doi.org/10.1039/B002031L
Article type
Communication
Submitted
10 Mar 2000
Accepted
23 May 2000
First published
13 Jun 2000

Chem. Commun., 2000, 1171-1172

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A new diastereoselective approach to simplified Dynemicin analogues

G. Guanti and R. Riva, Chem. Commun., 2000, 1171 DOI: 10.1039/B002031L

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