Optimization of enantiocontrol in cis-selective cyclopropanation reactions catalyzed by dirhodium(ii) tetrakis[alkyl 2-oxaazetidine-4(S)-carboxylates]
Abstract
Both intermolecular and macrocyclic intramolecular
cyclopropanation reactions occur with greater selectivity for the
cis-(Z)-diastereoisomer than for the
trans-(E)-diastereomer in reactions catalyzed by chiral
dirhodium(II) azetidinone-carboxylates; the influence of the
catalyst’s