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Issue 9, 2000
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Unique sodium-caged structure of a potent endothelin-1 inhibitor: crystal structure of BQ123 sodium salt, cyclo(-d-Trp-d-Asp-Pro-d-Val-Leu-)·Na+

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Abstract

The crystal structure of cyclo(D-Trp-D-Asp-Pro-D-Val-Leu-)·Na+, a potent endothelin-1 antagonist, showed four conformational isomers and two Na+-caged structures in pairs.

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Article information


Submitted
28 Nov 1999
Accepted
20 Mar 2000
First published
17 Apr 2000

Chem. Commun., 2000, 743-744
Article type
Communication

Unique sodium-caged structure of a potent endothelin-1 inhibitor: crystal structure of BQ123 sodium salt, cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu-)·Na+

M. Doi, T. Ishida, Y. Katsuya, Y. Mezaki, M. Sasaki, A. Terashima, T. Taniguchi, H. Hasegawa and M. Shiono, Chem. Commun., 2000, 743
DOI: 10.1039/A909413J

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