Issue 20, 1999

Studies on enzymatic hydrolysis of thymidin-3′-yl thymidin-5′-yl phosphorofluoridates and the corresponding phosphorothiofluoridates

Abstract

Spleen or snake venom nuclease-assisted cleavage of P–F bonds in nucleotides bearing a phosphorofluoridate moiety occurs at negatively charged phosphates only.

Article information

Article type
Paper

Chem. Commun., 1999, 2115-2116

Studies on enzymatic hydrolysis of thymidin-3′-yl thymidin-5′-yl phosphorofluoridates and the corresponding phosphorothiofluoridates

K. Misiura, W. J. Stec, M. Bollmark and J. Stawinski, Chem. Commun., 1999, 2115 DOI: 10.1039/A906659D

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