Issue 22, 1999

Synthesis of racemic brevioxime

Abstract

Amine hydrochloride 12 and β-keto thioester 16 were coupled and treated with TFA; the resulting alcohols 18 were oxidized and converted into a mixture of oximes 20, from which the major product, racemic brevioxime 1, was isolated.

Article information

Article type
Paper

Chem. Commun., 1999, 2251-2252

Synthesis of racemic brevioxime

D. L. J. Clive and S. Hisaindee, Chem. Commun., 1999, 2251 DOI: 10.1039/A906579B

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