Issue 13, 1997
From the journal:

Chemical Communications

In situ generation of methylphosphonamidites for synthesis of oligonucleotide methylphosphonates

Zhaoda Zhang,   Alexandra Nichols,   Jimmy X. Tang  and  Jin Yan Tang  

Abstract

5′-DMT-nucleoside methylphosphonamidites are generated in situ by selective activation of methylbis-(pyrrolidino)phosphine 1, and used effectively in the automated synthesis of oligonucleotide methylphosphonates.

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Article information

DOI
https://doi.org/10.1039/A702551C
Article type
Paper

Chem. Commun., 1997, 1235-1236

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In situ generation of methylphosphonamidites for synthesis of oligonucleotide methylphosphonates

Z. Zhang, A. Nichols, J. X. Tang and J. Yan Tang, Chem. Commun., 1997, 1235 DOI: 10.1039/A702551C

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