(R)- and (S)-enantioselective lithiation of (arene)tricarbonylchromium acetal complexes with chiral alkyllithiums
Abstract
The lithiation of (arene)tricarbonylchromium acetal complexes with the organolithium reagents derived from (1R)-menthyl chloride and (1R)-8-phenylmenthyl chloride occurs at the pro-R site (up to 70% ee) and the pro-S(up to 80% ee), respectively.