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Issue 19, 1996
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Oligonucleotides containing 7- or 8-methyl-7-deazaguanine: steric requirements of major groove substituents on the DNA structure

Abstract

Methyl groups in alternating octanucleotides containing 7-methyl-7-deazaguanine and cytosine have steric freedom and maintain the B-DNA structure, whereas the isomeric-8-methyl-7-deazaguanine causes a B–Z transition.

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Article information


Chem. Commun., 1996, 2263-2264
Article type
Paper

Oligonucleotides containing 7- or 8-methyl-7-deazaguanine: steric requirements of major groove substituents on the DNA structure

F. Seela and Y. Chen, Chem. Commun., 1996, 2263
DOI: 10.1039/CC9960002263

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