Synthesis of optically active macrocycles consisting of helical chiral unit 1,12-dimethylbenzo[c]phenanthrene-5,8-dicarboxylate as a novel chiral building block
Abstract
Optically pure 1,12-dimethylbenzo[c]phenanthrene-5,8-dicarboxylic acid 1 is prepared in gram quantities, and a series of macrocycles consisting of the helical chiral unit are synthesized.