Issue 6, 1996

Stereospecific synthesis of chiral alkinylogous amino acids

Abstract

tert-Butoxycarbonyl(Boc)-protected α-amino aldehydes, conventionally prepared from the corresponding(S)-α-amino acid, are converted via the Corey–Fuchs reaction into the N-protected alkinylogous amino acids, which on deprotection yield the corresponding enantiomerically pure acids.

Article information

Article type
Paper

Chem. Commun., 1996, 733-734

Stereospecific synthesis of chiral alkinylogous amino acids

M. T. Reetz, T. J. Strack, J. Kanand and R. Goddard, Chem. Commun., 1996, 733 DOI: 10.1039/CC9960000733

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