Issue 13, 1995

The first enantioselective synthesis of isoflavonoids: (R)- and (S)-isoflavans

Abstract

α-Benzylation of (+)- and (–)-N-phenylacetyl imidazolidinones with 2-O-methoxymethylbenzyl bromide, followed by reductive removal of the chiral auxiliary and cyclization, leads to isoflavans in excellent enantiomeric excess and yield.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1995, 1317-1318

The first enantioselective synthesis of isoflavonoids: (R)- and (S)-isoflavans

M. Versteeg, B. C. B. Bezuidenhoudt, D. Ferreira and K. J. Swart, J. Chem. Soc., Chem. Commun., 1995, 1317 DOI: 10.1039/C39950001317

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