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Issue 16, 1993
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Studies on the stereospecificity of the clavaminic acid synthase catalysed hydroxylation reaction

Abstract

Incubation of (2S,3S)-5-guanidino[2,3-2H2]-2-(2′-oxoazetidin-1′-yl)pentanoic acid and (2S,3R)-5-guanidino-[3-2H1]-2-(2′-oxoazetidin-1′-yl)pentanoic acid with clavaminic acid synthase resulted in highly stereospecific hydroxylation at C-3, with removal of the pro-R hydrogen or deuterium, respectively.

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Article type: Paper
DOI: 10.1039/C39930001301
Citation: J. Chem. Soc., Chem. Commun., 1993,0, 1301-1302

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    Studies on the stereospecificity of the clavaminic acid synthase catalysed hydroxylation reaction

    J. E. Baldwin, K. D. Merritt, C. J. Schofield, S. W. Elson and K. H. Baggaley, J. Chem. Soc., Chem. Commun., 1993, 0, 1301
    DOI: 10.1039/C39930001301

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