SCHEDULED MAINTENANCE
(±)-α-Amino-β-phenylpropionitrile was hydrated enantioselectively, in a basic aqueous medium, using (–)-5β-(2-hydroxypropan-2-yl)-3α-cyano-2α-methylcyclohexanone as a chiral catalyst 6, with 42% enantiomeric excess at half completion.
Z. Tadros, P. H. Lagriffoul, L. Mion, J. Taillades and A. Commeyras, J. Chem. Soc., Chem. Commun., 1991, 1373 DOI: 10.1039/C39910001373
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