Issue 15, 1990

β-Ketoester dianions as regiospecific enolate equivalents for N-substituted pyrrolidin-3-ones

Abstract

Double deprotonation of β-ketoester (6) gives dianion (7) which serves as a synthetic equivalent of the regiospecific ketone enolate (3), providing a synthetic entry to 2-substituted pyrrolidin-3-ones (9) and (10).

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1990, 1047-1048

β-Ketoester dianions as regiospecific enolate equivalents for N-substituted pyrrolidin-3-ones

M. Giles, M. S. Hadley and T. Gallagher, J. Chem. Soc., Chem. Commun., 1990, 1047 DOI: 10.1039/C39900001047

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