Issue 12, 1990

Synthesis and reactivity of a novel oxazolo[2, 3-c][1,4]benzodiazepine ring system with DNA recognition potential: a new class of anthramycins

Abstract

The new carbinolamine-containing oxazolo[2,3-c][1,4]benzodiazepine ring system has been synthesized, and its reactivity and stability have been compared with properties of the analogous pyrrolo[2,1-c][1,4]benzodiazepine system found in the DNA-binding anthramycin antitumour antibiotics.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1990, 874-876

Synthesis and reactivity of a novel oxazolo[2, 3-c][1,4]benzodiazepine ring system with DNA recognition potential: a new class of anthramycins

D. E. Thurston, G. B. Jones and M. E. Davis, J. Chem. Soc., Chem. Commun., 1990, 874 DOI: 10.1039/C39900000874

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