Optically active pentadienyltin reagent and its application to asymmetric synthesis of (R)-7,11-dideoxydaunomycinone
Abstract
Highly optically active 2-substituted 2,4-pentadienyltin reagent was synthesised and applied to an efficient asymmetric synthesis of (R)-7,11-dideoxydaunomycinone by means of tandem Michael/Diels–Alder reaction in a key step.