Issue 7, 1989

New insights into the mechanism of the cis-platin–guanosine 5′-monophosphate reaction

Abstract

The reaction of cis-diamminedichloroplatinum(II) and cis-dichloroethylenediamineplatinum(II) with guanosine 5′-monophosphate (GMP) proceed through the formation of a N-7-bound mono(GMP) complex which undergoes further reaction with the initial plantinum substrate and another GMP molecule to form a GMP-bridged diplatinum(II,II) species and a bis(GMP) complex.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1989, 432-433

New insights into the mechanism of the cis-platin–guanosine 5′-monophosphate reaction

N. Goswami, L. L. Bennett-Slavin and R. N. Bose, J. Chem. Soc., Chem. Commun., 1989, 432 DOI: 10.1039/C39890000432

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