A new synthesis of oxa- and carba-cepham skeletons was developed by use of palladium catalysed ene–halogenocyclization followed by treatment with 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU).
M. Mori, N. Kanda and Y. Ban, J. Chem. Soc., Chem. Commun., 1986, 1375 DOI: 10.1039/C39860001375
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