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Issue 2, 1985

A concise synthesis of (±)-vincadifformine and related Aspidosperma alkaloids (±)-desethylvincadifformine, (±)-ibophyllidine, (±)-20-epi-ibophyllidine, and (±)-desethylibophyllidine

Abstract

An expeditious total synthesis of (±)-vincadifformine (9) and related Aspidosperma alkaloids (±)-desethylvincadifformine (10), (±)-ibophyllidine (11), (±)-20-epi-ibophyllidine (12), and (±)-desethylibophyllidine (13)via condensation of a common indole-2-acrylate precursor (2) and an appropriate amine (4) followed by acidic treatment is reported.

Article information


J. Chem. Soc., Chem. Commun., 1985, 88-89
Article type
Paper

A concise synthesis of (±)-vincadifformine and related Aspidosperma alkaloids (±)-desethylvincadifformine, (±)-ibophyllidine, (±)-20-epi-ibophyllidine, and (±)-desethylibophyllidine

M. Barsi, B. C. Das, J. Fourrey and R. Sundaramoorthi, J. Chem. Soc., Chem. Commun., 1985, 88 DOI: 10.1039/C39850000088

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