In the biosynthesis of ristocetin by Nocardia Iurida it has been shown that m,m′-dihydroxyphenylglycine and p-methyl-m,m′- dihydroxyphenylglycine can be derived from acetic acid, whereas p-hydroxyphenylglycine and β-hydroxytyrosine are derived from tyrosine.
S. J. Hammond, D. H. Williams and R. V. Nielsen, J. Chem. Soc., Chem. Commun., 1983, 116 DOI: 10.1039/C39830000116
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