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Issue 18, 1974
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Acid-catalysed decomposition of N-nitroso-2-pyrrolidone—a rare example of amide hydrolysis via SN2 displacement on the N-conjugate acid

Abstract

The first definite proof that amide hydrolysis may proceed via a direct SN2 displacement on the N-conjugate acid is reported for the acid-catalysed decomposition of N-nitroso-2-pyrrolidone.

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Article information


J. Chem. Soc., Chem. Commun., 1974, 748-749
Article type
Paper

Acid-catalysed decomposition of N-nitroso-2-pyrrolidone—a rare example of amide hydrolysis via SN2 displacement on the N-conjugate acid

B. C. Challis and S. P. Jones, J. Chem. Soc., Chem. Commun., 1974, 748
DOI: 10.1039/C39740000748

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