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Issue 11, 1974
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A key intermediate for the synthesis of some nuclear analogues of the penicillins and cephalosporins

Abstract

Starting with L-cysteine and using the recently developed photolytic Wolff rearrangement of 3-diazopyrrolidine-2,4-diones for the synthesis of β-lactams, an intermediate has been prepared which should allow new families of β-lactam antibiotics to be synthesised.

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Article information


J. Chem. Soc., Chem. Commun., 1974, 419-420
Article type
Paper

A key intermediate for the synthesis of some nuclear analogues of the penicillins and cephalosporins

J. R. Hlubucek and G. Lowe, J. Chem. Soc., Chem. Commun., 1974, 419
DOI: 10.1039/C39740000419

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