Jump to main content
Jump to site search

Issue 2, 2021

Gold nanoparticles to enhance ophthalmic imaging

Author affiliations

Abstract

The use of gold nanoparticles as diagnostic tools is burgeoning, especially in the cancer community with a focus on theranostic applications to both cancer diagnosis and treatment. Gold nanoparticles have also demonstrated great potential for use in diagnostic and therapeutic approaches in ophthalmology. Although many ophthalmic imaging modalities are available, there is still a considerable unmet need, in particular for ophthalmic molecular imaging for the early detection of eye disease before morphological changes are more grossly visible. An understanding of how gold nanoparticles are leveraged in other fields could inform new ways they could be utilized in ophthalmology. In this paper, we review current ophthalmic imaging techniques and then identify optical coherence tomography (OCT) and photoacoustic imaging (PAI) as the most promising technologies amenable to the use of gold nanoparticles for molecular imaging. Within this context, the development of gold nanoparticles as OCT and PAI contrast agents are reviewed, with the most recent developments described in detail.

Graphical abstract: Gold nanoparticles to enhance ophthalmic imaging

Article information


Submitted
28 Jun 2020
Accepted
02 Oct 2020
First published
08 Oct 2020

Biomater. Sci., 2021,9, 367-390
Article type
Review Article

Gold nanoparticles to enhance ophthalmic imaging

F. Chen, P. Si, A. de la Zerda, J. V. Jokerst and D. Myung, Biomater. Sci., 2021, 9, 367 DOI: 10.1039/D0BM01063D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements