Issue 3, 2019

Platelet-derived nanovesicles for hemostasis without release of pro-inflammatory cytokines

Abstract

Natural platelet-derived nanovesicles with a vacant core were prepared by hypotonic sonication. The nanovesicles efficiently formed platelet-like aggregates using membrane protein in the presence of thrombin and calcium chloride without a notable release of pro-inflammatory cytokines. These natural and biocompatible platelet-derived nanovesicles have great potential as biomaterials for inflammation-free injectable hemostasis.

Graphical abstract: Platelet-derived nanovesicles for hemostasis without release of pro-inflammatory cytokines

Supplementary files

Article information

Article type
Communication
Submitted
15 Nov 2018
Accepted
24 Dec 2018
First published
09 Jan 2019

Biomater. Sci., 2019,7, 856-859

Platelet-derived nanovesicles for hemostasis without release of pro-inflammatory cytokines

H. Jung, Y. Y. Kang and H. Mok, Biomater. Sci., 2019, 7, 856 DOI: 10.1039/C8BM01480A

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