Immunomodulatory vasoactive intestinal peptide amphiphile micelles

Rui Zhang; Caitlin N. Leeper; Xiaofei Wang; Tommi A. White; Bret D. Ulery

doi:10.1039/C8BM00466H

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Immunomodulatory vasoactive intestinal peptide amphiphile micelles†

Rui Zhang,^a Caitlin N. Leeper,^a Xiaofei Wang,^a Tommi A. White^b and Bret D. Ulery

*^ac

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* Corresponding authors

^a Department of Chemical Engineering, University of Missouri, Columbia, MO 65211, USA
E-mail: uleryb@missouri.edu

^b Department of Biochemistry, University of Missouri, Columbia, MO 65211, USA

^c Department of Bioengineering, University of Missouri, Columbia, MO 65211, USA

Abstract

Two different vasoactive intestinal peptide (VIP) amphiphiles have been formulated which readily form micelles of varying shapes. Interestingly, VIP micelle structure has been found to directly correlate to anti-inflammatory behavior providing evidence that these biomaterials can serve as a promising new therapeutic modality.

This article is part of the themed collection: Biomaterial Interactions with the Immune System

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DOI: https://doi.org/10.1039/C8BM00466H
Article type: Communication
Submitted: 26 Apr 2018
Accepted: 14 May 2018
First published: 15 May 2018

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Biomater. Sci., 2018,6, 1717-1722

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Immunomodulatory vasoactive intestinal peptide amphiphile micelles

R. Zhang, C. N. Leeper, X. Wang, T. A. White and B. D. Ulery, Biomater. Sci., 2018, 6, 1717 DOI: 10.1039/C8BM00466H

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Biomaterials Science

Immunomodulatory vasoactive intestinal peptide amphiphile micelles†

Abstract

Supplementary files

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Immunomodulatory vasoactive intestinal peptide amphiphile micelles

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