Jump to main content
Jump to site search

Issue 2, 2016
Previous Article Next Article

A convenient process to fabricate gelatin modified porous PLLA materials with high hydrophilicity and strength

Author affiliations

Abstract

PLLA porous materials with high porosity were prepared by a gradual precipitation method and further modified by using different concentrations of gelatin aqueous solutions. Therefore, porous materials with different contents of gelatin coating were obtained. The micro morphology, crystallization, thermal performance, hydrophilicity and mechanical properties of the materials were evaluated by scanning electron microscopy (SEM), differential scanning calorimetry (DSC), X-ray diffraction (XRD), thermogravimetric analysis (TGA), water uptake ability tests and compression tests. It was found that the modified materials were formed by the stacking of nanosheets. The materials can maintain more than 80% porosity, high water uptake abilities and fast water uptake rates after modification. The compressive moduli of the materials were significantly improved from the initial sample with a value of 0.57 MPa to 46.41 MPa with gelatin modification. Due to the high porosity of materials, interconnected pore structures, and good surface hydrophilicity, the materials were expected to be widely used in the field of tissue engineering scaffolds, especially for bone substitutes, mainly due to their tunable and excellent mechanical properties.

Graphical abstract: A convenient process to fabricate gelatin modified porous PLLA materials with high hydrophilicity and strength

Back to tab navigation

Supplementary files

Article information


Submitted
24 Sep 2015
Accepted
31 Oct 2015
First published
16 Nov 2015

Biomater. Sci., 2016,4, 310-318
Article type
Paper

A convenient process to fabricate gelatin modified porous PLLA materials with high hydrophilicity and strength

G. Yin, D. Zhao, Y. Ren, L. Zhang, Z. Zhou and Q. Li, Biomater. Sci., 2016, 4, 310
DOI: 10.1039/C5BM00414D

Social activity

Search articles by author

Spotlight

Advertisements