Jump to main content
Jump to site search

Issue 3, 2013
Previous Article Next Article

Three-dimensional cell culture based on microfluidic techniques to mimic living tissues

Author affiliations

Abstract

This mini-review consists of microfluidic fabrication methods of cellular spheroids and cell-laden hydrogels, and their applications for tissue engineering. Using microfluidic devices, cellular spheroids and cell-laden hydrogels with controllable design are formed reproducibly. Owing to their size uniformity, they are used as building blocks for bottom–up tissue engineering to construct uniform and arbitrarily shaped tissues. Thus, cellular spheroids and cell-laden hydrogels based on microfluidic techniques are powerful tools to create tissues for human implantation and the treatment of diseases.

Graphical abstract: Three-dimensional cell culture based on microfluidic techniques to mimic living tissues

Back to tab navigation

Publication details

The article was received on 13 Aug 2012, accepted on 06 Oct 2012 and first published on 20 Nov 2012


Article type: Minireview
DOI: 10.1039/C2BM00117A
Citation: Biomater. Sci., 2013,1, 257-264

  •   Request permissions

    Three-dimensional cell culture based on microfluidic techniques to mimic living tissues

    Y. Morimoto and S. Takeuchi, Biomater. Sci., 2013, 1, 257
    DOI: 10.1039/C2BM00117A

Search articles by author

Spotlight

Advertisements