Jump to main content
Jump to site search

Issue 1, 2018
Previous Article Next Article

Fast screening of flavonoids from switchgrass and Mikania micrantha by liquid chromatography hybrid-ion trap time-of-flight mass spectrometry

Author affiliations

Abstract

Weeds contain flavonoids that have antioxygenation, circulation improvement, and cholesterol-lowering effects. The novel and widely applicable method of liquid chromatography hybrid-ion trap time-of-flight mass spectrometry (LC/MS-IT-TOF) was established to quickly screen non-target flavonoid components from weeds in this study. This method required two steps, the detection of characteristic ions of the flavonoid components and their identification by comparison of their manual fragments. Then all non-target and semi-target flavonoid components could be directly determined via automatically screening out the characteristic fragments. This method was successfully applied for the fast determination of flavonoid components in the stem extract of switchgrass. One glycoside of isorhamnetin (isorhamnetin-3-O-rutinoside) and six glycosides of quercetin (quercetin-3-O-galactoside, quercetin-3-O-glucoside, rutin, quercetin-3-O-xyloside, quercetin-3-O-arabinoside, and quercetin-3-O-rhamnoside) were detected in switchgrass. In addition, syringaresinol hexoside was also found in this weed. Among these compounds, six (quercetin-3-O-galactoside, quercetin-3-O-glucoside, quercetin-3-O-xyloside, quercetin-3-O-arabinoside, isorhamnetin-3-O-rutinoside and syringaresinol hexoside) were first found in switchgrass. In Mikania micrantha, three more flavonoid components were detected than that in our previous study. This efficient method could be universally applied for the identification of components in some complex matrix samples like food samples and plant samples.

Graphical abstract: Fast screening of flavonoids from switchgrass and Mikania micrantha by liquid chromatography hybrid-ion trap time-of-flight mass spectrometry

Back to tab navigation

Publication details

The article was received on 02 Sep 2017, accepted on 26 Nov 2017 and first published on 11 Dec 2017


Article type: Paper
DOI: 10.1039/C7AY02103H
Anal. Methods, 2018,10, 109-122

  •   Request permissions

    Fast screening of flavonoids from switchgrass and Mikania micrantha by liquid chromatography hybrid-ion trap time-of-flight mass spectrometry

    A. Li, X. Hou and Y. Wei, Anal. Methods, 2018, 10, 109
    DOI: 10.1039/C7AY02103H

Search articles by author

Spotlight

Advertisements