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Issue 15, 2016
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Determination of glutathione based on NiPd nanoparticles mediated with acetaminophen

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Abstract

A new method for determination of glutathione (GSH) was carried out with acetaminophen (AAP) mediation on a NiPd nanoparticle modified electrode. The as-prepared sensor exhibited excellent electrocatalytic activity for determining GSH with a good linear correlation with GSH concentration in a broad range from 0.5 to 3000 μM, a high detection sensitivity (481.69 μA mM−1 cm−2), and a low detection limit of 0.5 μM. The mechanism for GSH oxidation was also investigated by cyclic voltammetry and linear sweep voltammetry. In addition, the proposed sensor was also successfully employed to detect GSH in real samples.

Graphical abstract: Determination of glutathione based on NiPd nanoparticles mediated with acetaminophen

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Publication details

The article was received on 19 Jan 2016, accepted on 05 Feb 2016 and first published on 17 Feb 2016


Article type: Paper
DOI: 10.1039/C6AY00171H
Citation: Anal. Methods, 2016,8, 3000-3005

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    Determination of glutathione based on NiPd nanoparticles mediated with acetaminophen

    H. Zhang, L. Zhang, Y. Ding, W. Zhang, X. Zhang, Y. Shen and F. Yang, Anal. Methods, 2016, 8, 3000
    DOI: 10.1039/C6AY00171H

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