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Issue 3, 2016
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Detection of sibutramine and phenolphthalein in functional foods using capillary electrophoresis

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Abstract

A simple method has been established for the simultaneous detection of sibutramine and phenolphthalein by using capillary electrophoresis. A mixture of 20 mM phosphate buffer and 20 mM sodium dodecyl sulfate was used as running buffer (pH 11.0). Analysis was carried out at a detection wavelength of 223 nm under a separation voltage of 25 kV at 20 °C. The limits of detection (LODs) were 0.03 μg mL−1 for sibutramine and 0.18 μg mL−1 for phenolphthalein. The linear ranges of the method were 0.1–50 μg mL−1 for sibutramine and 0.8–50 μg mL−1 for phenolphthalein. The proposed method has been successfully applied for the detection of the two target chemicals in functional foods, with satisfactory recovery ranging from 95.3% to 103.4%.

Graphical abstract: Detection of sibutramine and phenolphthalein in functional foods using capillary electrophoresis

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Publication details

The article was received on 12 Nov 2015, accepted on 07 Dec 2015 and first published on 09 Dec 2015


Article type: Paper
DOI: 10.1039/C5AY02973B
Anal. Methods, 2016,8, 621-626

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    Detection of sibutramine and phenolphthalein in functional foods using capillary electrophoresis

    D. Wang, R. Man, M. Shu, H. Liu, Y. Gao and F. Luan, Anal. Methods, 2016, 8, 621
    DOI: 10.1039/C5AY02973B

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