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Issue 17, 2014
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Are glycan biosensors an alternative to glycan microarrays?

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Abstract

Complex carbohydrates (glycans) play an important role in nature and study of their interaction with proteins or intact cells can be useful for understanding many physiological and pathological processes. Such interactions have been successfully interrogated in a highly parallel way using glycan microarrays, but this technique has some limitations. Thus, in recent years glycan biosensors in numerous progressive configurations have been developed offering distinct advantages compared to glycan microarrays. Thus, in this review advances achieved in the field of label-free glycan biosensors are discussed.

Graphical abstract: Are glycan biosensors an alternative to glycan microarrays?

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Publication details

The article was received on 18 Mar 2014, accepted on 30 May 2014 and first published on 09 Jul 2014


Article type: Minireview
DOI: 10.1039/C4AY00692E
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Anal. Methods, 2014,6, 6610-6620

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    Are glycan biosensors an alternative to glycan microarrays?

    A. Hushegyi and J. Tkac, Anal. Methods, 2014, 6, 6610
    DOI: 10.1039/C4AY00692E

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