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Issue 1, 2014
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Size separation of biomolecules and bioparticles using micro/nanofabricated structures

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Abstract

Reports of novel micro/nanostructures designed to separate biomacromolecules and bioparticles are increasing in number, and these studies have greatly advanced our understanding of nanoscale fluidics and nanoparticle behavior in confined channels. This review is aimed at summarizing previous developments in micro/nanofabricated systems for nanoparticle separations. These are discussed in three groups based on architecture, namely, micro/nanopillar array structures, nanoplane gap structures and artificial nanoporous membranes.

Graphical abstract: Size separation of biomolecules and bioparticles using micro/nanofabricated structures

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Article information


Submitted
08 Aug 2013
Accepted
17 Nov 2013
First published
28 Nov 2013

Anal. Methods, 2014,6, 27-37
Article type
Critical Review

Size separation of biomolecules and bioparticles using micro/nanofabricated structures

J. Xuan and M. L. Lee, Anal. Methods, 2014, 6, 27
DOI: 10.1039/C3AY41364K

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