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Issue 9, 2013
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Design and synthesis of a fluorescent probe based on the “on–off” behavior of the dansyl group through controlling quenching efficiency of the cyanopyranyl group by interaction with proteins

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Abstract

A new fluorescent probe displayed a large increase of fluorescence emission upon binding to proteins due to the cancellation of dansyl fluorescence quenching by the cyanopyranyl moiety. To take advantage of this phenomenon, qualitative and quantitative analyses of proteins were performed in the solution or in the gel for electrophoresis.

Graphical abstract: Design and synthesis of a fluorescent probe based on the “on–off” behavior of the dansyl group through controlling quenching efficiency of the cyanopyranyl group by interaction with proteins

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Publication details

The article was received on 16 Nov 2012, accepted on 17 Mar 2013 and first published on 18 Mar 2013


Article type: Communication
DOI: 10.1039/C3AY26412B
Anal. Methods, 2013,5, 2174-2177

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    Design and synthesis of a fluorescent probe based on the “on–off” behavior of the dansyl group through controlling quenching efficiency of the cyanopyranyl group by interaction with proteins

    Y. Suzuki, Anal. Methods, 2013, 5, 2174
    DOI: 10.1039/C3AY26412B

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